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Filename Biodefense-and-Emerging-Infectious-Diseases.pdf
filesize 671.43 kB
Version 1
Date added October 31, 2014
Downloaded 2242 times
Category Biofuels, Energy Security, Transportation Energy
year 2008
author Robert J. Meagher, Anson V. Hatch, Ronald F. Renzi, Anup K. Singh

Sandia researchers have created an integrated, portable diagnostic device suitable for detecting biological toxins in bodily fluids. At the heart of the device, which is known as the rapid, automated point-of-care system, is an electrophoretic immunoassay with integrated sample cleanup and preconcentration, enabling the detection of toxins such as ricin, Shiga toxin, and Staphylococcal enterotoxin B with micromolar to picomolar sensitivity. This device can be readily used to detect proteinaceous biomarkers of many other diseases and represents the next generation of diagnostic instruments that are capable of making rapid and quantitative measurements of multiple analytes simultaneously.